CINRYZE (C1 esterase inhibitor [human]) is an injectable prescription medicine that is used to help prevent swelling and/or painful attacks in teenagers and adults with Hereditary Angioedema (HAE).
Important Safety Information
You should not use CINRYZE if you have had life-threatening immediate hypersensitivity reactions, including anaphylaxis to the product.
Tell your healthcare provider about all of your medical conditions, including if you:
•have an indwelling catheter/access device in one of your veins.
•have a history of blood clots, heart disease, or stroke.
•are taking birth control pills or androgens.
•are pregnant or planning to become pregnant. It is not known if CINRYZE can harm your unborn baby.
•are breastfeeding or plan to breastfeed. It is not known if CINRYZE passes into your milk and if it can harm your baby.
Allergic reactions may occur with CINRYZE. Call your healthcare provider or get emergency support services right away if you have any of the following symptoms:
•wheezing
•difficulty breathing
•chest tightness
•turning blue (look at lips and gums)
•fast heartbeat
•swelling of the face
•faintness
•rash
•hives
Serious blood clots may occur with CINRYZE. Call your healthcare provider or get emergency support services right away if you have any of the following symptoms:
•pain and/or swelling of an arm or leg with warmth over the affected area
•discoloration of an arm or leg
•unexplained shortness of breath
•chest pain or discomfort that worsens on deep breathing
•unexplained rapid heart rate
•numbness or weakness on one side of the body
Because CINRYZE is made from human blood, it may carry a risk of transmitting infectious agents, e.g., viruses and, theoretically, the Creutzfeldt-Jakob disease (CJD) agent.