Gio57 schreef op 28 augustus 2020 13:40:
Basel :
Intervention/treatment
Active Comparator: active treatment arm
treatment with conestat alfa in addition to standarf of care
Drug: Conestat alfa
Conestat alfa (8400 Units (U) followed by 4200 U every 8 hours, 9 administrations in total) will be administered as a slow intravenous injection (5-10 minutes) over a 72 hour period.
USA :
Arm Intervention/treatment
Experimental: Ruconest
Patients receive (150 U/ml) of Ruconest at a 50 U/kg dose (max dose of 4200 U) as a slow intravenous injection via a peripheral every 12 hours; for 4 days. A total of 8 doses will be administered.
Drug: Ruconest
Patients will be randomized to Ruconest or Standard of Care
Zoek de verschillen